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(Download) "Regulation of Gene Expression" by Gary H. Perdew, Jack P. Vanden Heuvel & Jeffrey M. Peters # Book PDF Kindle ePub Free

Regulation of Gene Expression

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eBook details

  • Title: Regulation of Gene Expression
  • Author : Gary H. Perdew, Jack P. Vanden Heuvel & Jeffrey M. Peters
  • Release Date : January 17, 2008
  • Genre: Life Sciences,Books,Science & Nature,Professional & Technical,Medical,
  • Pages : * pages
  • Size : 5372 KB

Description

Regulation of Gene Expression: Molecular Mechanisms presents a comprehensive overview of methods and approaches for characterizing mechanisms of gene regulation. The text is appropriate both as a graduate textbook and a standard laboratory reference and provides the essential groundwork for an advanced understanding of the various mechanisms that may result in altered activity of a specific cell protein.

Each of three sections explores mechanisms of gene regulation and expression, and presents methods and protocols for achieving specific experimental goals. Part I focuses on approaches for studying control of mRNA expression and determining target genes for a given transcription copy. Part II outlines the methods for determining how proteins can regulate each other by mediating synthesis, degradation, protein-protein interactions, and posttranslational modification. Part III explores how gene targeting techniques in mice can provide insight into protein function. This volume provides a clear, concise overview of the protocols and techniques used to examine chemically or disease-mediated alterations in gene expression in mammalian systems.


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